Dilated cardiomyopathy in Indian children.
Indian Heart J
;
2003 Mar-Apr; 55(2): 147-51
Article
Dans Anglais
| IMSEAR
| ID: sea-3654
ABSTRACT
BACKGROUND:
The aim of this study was to ascertain the clinical course and prognosis of dilated cardiomyopathy in Indian children. METHODS ANDRESULTS:
The records of 82 children with dilated cardiomyopathy (50 males), less than 12 years of age (mean age 2.9+/-3.07 years), were retrospectively reviewed. Clinical variables, laboratory parameters, and serial echocardiograms were analyzed. On a mean follow-up of 25.09 months (range 15 days-118 months), 9 out of 78 patients died (11.5%) (CI 4.5%-18.5%). Mortality was 25% (6/24) in infants but the actuarial survival was 87% at 5 years in those diagnosed beyond infancy. Serial echocardiograms of 66 patients (80%) were available. Of these, 39 patients (59%) (CI 47%-70%) improved, 12 (18%) (CI 9%-27%) deteriorated or died, and 15 (23%) (CI 13%-33%) remained unchanged during the follow-up. Among the prognostic variables, only age less than 1 year, higher cardiothoracic ratio, and a higher ratio of left ventricular diastolic dimension/posterior wall thickness was associated with a poor outcome on univariate analysis.CONCLUSIONS:
Dilated cardiomyopathy in children pursues a heterogeneous course with a high mortality in infants. A large number of children diagnosed beyond infancy improve or recover. Further characterization of prognostic variables is warranted.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Débit systolique
/
Femelle
/
Humains
/
Mâle
/
Échocardiographie
/
Cardiomyopathie dilatée
/
Analyse de survie
/
Enfant
/
Enfant d'âge préscolaire
/
Protection de l'enfance
Type d'étude:
Étude observationnelle
/
Étude pronostique
Pays comme sujet:
Asie
langue:
Anglais
Texte intégral:
Indian heart j
Année:
2003
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS