Comparison study of combined DTPw-HB vaccines and separate administration of DTPw and HB vaccines in Thai children.
Asian Pac J Allergy Immunol
;
1999 Jun; 17(2): 113-20
Article
Dans Anglais
| IMSEAR
| ID: sea-36812
ABSTRACT
The safety, immunogenicity and tolerability of two different DTPw-HBV combination vaccines, containing 5 and 10 microg of HBsAg; were investigated in comparison with separate administration of DTPw and HBV (10 microg of HBsAg). A three dose primary vaccination course at 2, 4 and 6 months of age was followed by a booster dose at 18 months. All vaccines were safe and well tolerated. The DTPw-HBV combination vaccine containing 10 microg of HBsAg elicited significantly higher anti-HBs titres than the other two vaccines after the primary and booster vaccination course. All vaccines elicited a high response against the other components. Based on these results, DTPw-HBV (10 microg HBsAg) was the most effective vaccine at this schedule.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Douleur
/
Phases du sommeil
/
Facteurs temps
/
Humains
/
Vaccin diphtérie-tétanos-coqueluche
/
Vaccination
/
Vaccins anti-hépatite B
/
Vaccins combinés
/
Érythème
/
Fièvre
Type d'étude:
Essai clinique contrôlé
langue:
Anglais
Texte intégral:
Asian Pac J Allergy Immunol
Année:
1999
Type:
Article
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