Lymphocyte subset T4/T8 ratio in systemic lupus erythematosus: correlation with disease activity, laboratory abnormalities and treatment.
Asian Pac J Allergy Immunol
;
1988 Jun; 6(1): 23-8
Article
Dans Anglais
| IMSEAR
| ID: sea-36977
ABSTRACT
Lymphocyte subsets were studied in forty-nine patients with SLE using monoclonal antibodies and flow cytometry. A decrease in T4+ reactive cells (helper/inducer) was the most frequent observation. Decreased T4/T8 ratios were seen in patients with increasing clinically active disease, patients with positive anti-DS-DNA, positive anti-RNP antibodies and patients with low CH50 activity. However, low T4/T8 ratios were seen in patients with negative anti-Sm. Low T4/T8 ratios were also observed in patients taking prednisone at more than 10 mg/day and in patients treated with immunosuppressive drugs.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Femelle
/
Humains
/
Mâle
/
Prednisone
/
Lymphocytes T
/
Lymphocytes T CD4/
/
Adolescent
/
Adulte
/
Immunosuppresseurs
/
Lupus érythémateux disséminé
langue:
Anglais
Texte intégral:
Asian Pac J Allergy Immunol
Année:
1988
Type:
Article
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