A cost-benefit of gnRH stimulation test in diagnosis of central precocious puberty (CPP).
Article
Dans Anglais
| IMSEAR
| ID: sea-38945
ABSTRACT
The GnRH stimulation test is the gold standard to diagnose central precocious puberty (CPP). Conventionally, we need at least 2 hours to finish the test which seems to be costly and time consuming. In this study, we described the pattern of LH and FSH levels during the GnRH test in 27 girls who presented with various degrees of precocious puberty. We found that the blood samples at 90 and 120 min after GnRH were not necessary. To save the cost of diagnosis, the basal LH/FSH ratio > 0.2, the 30 min LH/FSH ratio after GnRH > 0.9 and the peak LH/FSH ratio > 1.0 can be used to diagnose CPP with positive predictive values (PPV) of 87.3, 89.4 and 93.8 per cent respectively.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Puberté précoce
/
Femelle
/
Humains
/
Hormone lutéinisante
/
Dosage radioimmunométrique
/
Enfant
/
Hormone de libération des gonadotrophines
/
Techniques de diagnostic endocrinien
/
Fécondostimulants féminins
/
Hormone folliculostimulante
Type d'étude:
Évaluation en économique de la santé
/
Étude pronostique
langue:
Anglais
Année:
2000
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS