Inappropriate prescription of allopurinol in a teaching hospital.
Article
Dans Anglais
| IMSEAR
| ID: sea-39647
ABSTRACT
BACKGROUND:
Allopurinol is a drug that is widely used to treat hyperuricemia, but it is often prescribed inappropriately.OBJECTIVE:
The authors conducted a study to look for the appropriate allopurinol prescription and diagnosis of gout in the out-patient clinics at a university hospital. MATERIAL ANDMETHOD:
One hundred and forty-five patients who were newly prescribed allopurinol (128 males and 17 females, mean +/- SD age of 58.5 +/-14.1 years) were enrolled in this study.RESULT:
Only 77 (53.1%) received allopurinol with appropriate indications. Thirty-eight patients (26.2%) did not have allopurinol dose adjustment according to the patients' creatinine clearance. Among 131 patients, prescribed allopurinol for the diagnosis of gout, only 55 (42.0%) were diagnosed in accordance with the American Rheumatism Association criteria.CONCLUSION:
Inappropriate use of allopurinol (both the indication and prescribed dosage) and inappropriate diagnosis of gout are major problems even in a large teaching hospital. An educational campaign program is warranted for achieving appropriate diagnosis of gout, and eliminating the inappropriate use of allopurinol.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Services de consultations externes des hôpitaux
/
Ordonnances médicamenteuses
/
Thaïlande
/
Types de pratiques des médecins
/
Sujet âgé
/
Femelle
/
Humains
/
Mâle
/
Allopurinol
/
Antigoutteux
Type d'étude:
Étude observationnelle
/
Étude pronostique
Pays comme sujet:
Asie
langue:
Anglais
Année:
2007
Type:
Article
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