Update in pathophysiology and histopathology of focal segmental glomerulosclerosis.
Article
Dans Anglais
| IMSEAR
| ID: sea-40091
ABSTRACT
Focal segmental glomerulosclerosis (FSGS) is the leading cause of nephrotic syndrome in an adult worldwide. The prevalence of FSGS is estimated as being 20-30% in adults over the age of 15 years and slightly higher (30-35%) in the elderly (age > 60 years). The diagnosis solely relies on pathologic findings, which sclerosis involves some, but not all glomeruli (focal), and sclerosis affects a portion, but not the entire, glomerular tuft (segmental). The pathogenesis remains inconclusive but podocyte injury has been postulated. Even though steroid is the mainstay treatment, only 20-40% of patients are complete respond.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Sujet âgé de 80 ans ou plus
/
Sujet âgé
/
Humains
/
Glomérulonéphrite segmentaire et focale
/
Adolescent
/
Adulte
/
Podocytes
/
Adulte d'âge moyen
/
Syndrome néphrotique
Limites du sujet:
Aged80
langue:
Anglais
Année:
2006
Type:
Article
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