Predictive factors of systemic embolism in patients with mitral stenosis in sinus rhythm.
Article
Dans Anglais
| IMSEAR
| ID: sea-40488
ABSTRACT
BACKGROUND:
Systemic embolism is one of the major complications in patients with mitral stenosis (MS) who are in atrial fibrillation; however, this serious complication can also occur in patients with MS in sinus rhythm.OBJECTIVE:
The purpose of the present study was to identify the predictive factors of systemic emboli in patients with MS in sinus rhythm. MATERIAL ANDMETHOD:
Twenty patients with MS in sinus rhythm with recent cerebral embolism and 32 with MS in sinus rhythm without any history of systemic embolism were studied between January 2004 and May 2006. Clinical and echocardiographic data were assessed using stepwise logistic regression for prediction of systemic embolism.RESULTS:
Age (odds ratio [OR], 1.14; 95% confidence interval [CI] 1.04-1.26) and left atrial spontaneous echo contrast (LASEC) grade 3+ and 4+ (OR, 46.42; 95% CI, 5.00-436.49) were associated with, and predictive of systemic emboli, whereas left atrial appendage contraction flow velocities, left atrial size and mitral valve area were not.CONCLUSION:
The present study demonstrates that age and LASEC are the major predictive factors of systemic embolism in patients with MS in sinus rhythm. It would therefore be prudent to give anticoagulants to patients in atrial fibrillation as well as to those in sinus rhythm at risk of systemic embolism.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Fibrillation auriculaire
/
Thromboembolie
/
Sujet âgé
/
Femelle
/
Humains
/
Mâle
/
Études transversales
/
Facteurs de risque
/
Indicateurs d'état de santé
/
Adolescent
Type d'étude:
Etude d'étiologie
/
Étude observationnelle
/
Étude de prévalence
/
Étude pronostique
/
Facteurs de risque
langue:
Anglais
Année:
2008
Type:
Article
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