Urinary symptoms and quality of life changes in Thai women with overactive bladder after tolterodine treatment.
Article
Dans Anglais
| IMSEAR
| ID: sea-41139
ABSTRACT
OBJECTIVES:
To study the urinary symptoms and quality of life changes in Thai women with overactive bladder (OAB) after tolterodine treatment. MATERIAL ANDMETHOD:
Thirty women (aged 30-77 years) diagnosed as having OAB at the Gynecology Clinic, King Chulalongkorn Memorial Hospital from January to April 2004 were included in the present study. Tolterodine 2 mg, twice daily was given. After 8 weeks treatment, changes in micturition diary variables and tolerability were determined. Short form 36 (SF36) questionaires (Thai version) were given before and after 8 weeks of treatment.RESULTS:
At 8 weeks, all micturition per day decreased from 16. 7 +/- 5. 3 to 6. 7 +/- 2.4 times per day. The number of nocturia episodes decreased from 5.4 +/- 4.2 to 1.1 +/- 1.0 times per night. The most common side effect was dry month in 5 cases (16.7%) with 2 cases reporting a moderate degree and 1 case with severe degree. Only one case (3.3%) withdrew from the present study due to a severe dry mouth. The SF-36 scores changed significantly in the domains of physical functioning, role function emotional, social function and mental heath.CONCLUSION:
Tolterodine was well tolerated and its effects improved the quality of life in Thai women with OAB.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Phénylpropanolamine
/
Qualité de vie
/
Thaïlande
/
Incontinence urinaire
/
Composés benzhydryliques
/
Sujet âgé
/
Femelle
/
Humains
/
Études prospectives
/
Enquêtes et questionnaires
Type d'étude:
Étude observationnelle
Pays comme sujet:
Asie
langue:
Anglais
Année:
2005
Type:
Article
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