Maintenance therapy with itraconazole after treatment of cryptococcal meningitis in the acquired immunodeficiency syndrome.
Article
Dans Anglais
| IMSEAR
| ID: sea-41974
ABSTRACT
We conducted a prospective, open trial to establish the efficacy of itraconazole 400 mg/d as maintenance treatment for cryptococcal meningitis in AIDS patients. Between February 1996 and May 1997, 50 patients were included for analysis. After a mean follow-up of 326 days, 2 of 38 patients (5.3 per cent) had relapses of symptomatic cryptococcal meningitis. Hepatotoxicity occurred in 2 cases. In conclusion, maintenance therapy with itraconazole 400 mg/d is effective in preventing recurrent cryptococcal meningitis.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Récidive
/
Femelle
/
Humains
/
Mâle
/
Études prospectives
/
Méningite cryptococcique
/
Infections opportunistes liées au SIDA
/
Itraconazole
/
Adulte
/
Antifongiques
Type d'étude:
Étude observationnelle
langue:
Anglais
Année:
1997
Type:
Article
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