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Multidrug-resistant tuberculosis: response to treatment.
Article Dans Anglais | IMSEAR | ID: sea-42012
ABSTRACT

OBJECTIVE:

We investigated clinical response and mortality rates in 18 HIV- negative patients with multidrug-resistant tuberculosis.

METHOD:

We obtained detailed data from our hospital on patients with multidrug - resistant tuberculosis defined as tuberculosis resistant at least to isoniazid and rifampicin. Therapeutic responses were evaluated by both microbiologic and clinical data.

RESULTS:

From January 1985 to December 1990, 18 HIV-negative patients were identified and treated. One patient committed suicide 1 week after receiving antituberculous drugs. Of the 17 patients, 10 (58.8%) had clinical response as well as microbiologic response, 6 (35.3%) were persisters during 24 months of follow-up, and 1 (5.8%) died after 30 months of treatment. The median follow-up for the patients was 87 weeks (range, 24 to 212). For those who responded well, there was no relapse.
Sujets)
Texte intégral: Disponible Indice: IMSEAR (Asie du Sud-Est) Sujet Principal: Thaïlande / Tuberculose pulmonaire / Femelle / Humains / Mâle / Adolescent / Résultat thérapeutique / Tuberculose multirésistante / Séronégativité VIH / Adulte Pays comme sujet: Asie langue: Anglais Année: 1996 Type: Article

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Texte intégral: Disponible Indice: IMSEAR (Asie du Sud-Est) Sujet Principal: Thaïlande / Tuberculose pulmonaire / Femelle / Humains / Mâle / Adolescent / Résultat thérapeutique / Tuberculose multirésistante / Séronégativité VIH / Adulte Pays comme sujet: Asie langue: Anglais Année: 1996 Type: Article