Multidrug-resistant tuberculosis: response to treatment.
Article
Dans Anglais
| IMSEAR
| ID: sea-42012
ABSTRACT
OBJECTIVE:
We investigated clinical response and mortality rates in 18 HIV- negative patients with multidrug-resistant tuberculosis.METHOD:
We obtained detailed data from our hospital on patients with multidrug - resistant tuberculosis defined as tuberculosis resistant at least to isoniazid and rifampicin. Therapeutic responses were evaluated by both microbiologic and clinical data.RESULTS:
From January 1985 to December 1990, 18 HIV-negative patients were identified and treated. One patient committed suicide 1 week after receiving antituberculous drugs. Of the 17 patients, 10 (58.8%) had clinical response as well as microbiologic response, 6 (35.3%) were persisters during 24 months of follow-up, and 1 (5.8%) died after 30 months of treatment. The median follow-up for the patients was 87 weeks (range, 24 to 212). For those who responded well, there was no relapse.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Thaïlande
/
Tuberculose pulmonaire
/
Femelle
/
Humains
/
Mâle
/
Adolescent
/
Résultat thérapeutique
/
Tuberculose multirésistante
/
Séronégativité VIH
/
Adulte
Pays comme sujet:
Asie
langue:
Anglais
Année:
1996
Type:
Article
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