High plasma branched-chain amino acids:aromatic amino acids ratio in children on the ketogenic diet: a mechanism in controlling epilepsy.
Article
Dans Anglais
| IMSEAR
| ID: sea-43162
ABSTRACT
BACKGROUND:
The authors proposed that ketogenic diets will produce an increase in the ratio of branched chain amino acids (BCAAs) and aromatic amino acids (BCAAs) in plasma of children who are on the diets. SUBJECTS ANDMETHOD:
A sample of plasma amino acids sample before initiation of fasting and on day 10 of the dietary treatment was obtained in patients with refractory epilepsy who were newly admitted for initiation of ketogenic diet. Plasma amino acids were determined by high performance liquid chromatography equipment.RESULTS:
There are 20 patients with refractory epilepsy participating in this study. Outcomes of ketogenic diet therapy were satisfactory. Nineteen cases out of 20 cases had a significantly higher ratio of plasma BCAAsARAAs during ketogenic diets than before the diet (P < 0.001).CONCLUSION:
The ketogenic diets produced an increased ratio of plasma BCAAsARAAs. Whether the increased ratio of plasma BCAAsARAAs plays an important role in controlling epilepsy is yet to be elucidated.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Femelle
/
Humains
/
Mâle
/
Enfant
/
Enfant d'âge préscolaire
/
Adolescent
/
Acides aminés aromatiques
/
Épilepsie
/
Acides aminés à chaine ramifiée
/
Nourrisson
langue:
Anglais
Année:
2004
Type:
Article
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