Histopathologic consistency between endometrial hyperplasia diagnosis from endometrial curettage and pathologic diagnoses from hysterectomy specimens.

ABSTRACT

OBJECTIVES: To evaluate the consistency between histopathology of endometrial hyperplasia (EMH) from endometrial curettage and those from the subsequent hysterectomy specimen. The co-incidental finding of endometrial carcinoma in patients with EMH was also studied. MATERIAL AND METHOD: All patients who had a diagnosis of EMH from the curettage procedure and underwent hysterectomy, between January 1995 and December 2004, were identified. The histopathology of the curettage specimens were compared to those of the hysterectomy specimens. RESULTS: The histopathologic subtypes of EMH from the curettage specimens of 46 patients included in the study were simple or complex hyperplasia in 30 cases and atypical simple or complex hyperplasia in 16 cases. The consistency rate of endometrial tissue from curettage and hysterectomy specimens was 41.3%. The consistency rates were 62.5% and 30.0% in patients with atypical EMH and EMH without atypia respectively. Eight cases (17.4%) of EMH also had co-incident endometrial carcinoma. CONCLUSION: The consistency rate of endometrial tissue from curettage and hysterectomy specimens was only modest. This rate was lower in EMH without atypia.