Prevalence of onychomycosis in patients with autoimmune diseases.
Article
Dans Anglais
| IMSEAR
| ID: sea-44377
ABSTRACT
BACKGROUND:
Onychomycosis is the most common nail disorder in adults. Many studies reported a higher prevalence of onychomycosis among particular patients, such as those with diabetes, poor peripheral circulation or immunosuppression. However, studies of the prevalence of onychomycosis in autoimmune patients who carry many of these predisposing factors have been limitedOBJECTIVE:
Study the prevalence of onychomycosis in autoimmune compared to non-autoimmune female patients. MATERIAL ANDMETHOD:
A cross-sectional study of the prevalence of onychomycosis in autoimmune patients and non-autoimmune female patients visiting a dermatology clinic over a period of 18 months. One hundred and sixty-five female autoimmune patients were enrolled.RESULTS:
The prevalence of onychomycosis in autoimmune patients was 10.2% (95%CI 6.5%, 15.9%) compared to 6.7% (95%CI 3.8%, 11.6%), in non-autoimmune patients (p > 0.05, 2-sided). Of vesiculobullous patients, mainly presenting with pemphigus and who were mostly on immunosuppressive medication, 24% had onychomycosis [p = 0.013; OR 4.39 (95%CI 1.27, 14.89)].CONCLUSION:
Exposure to humid microenvironments was an important factor in the occurrence of onychomycosis (p < 0.05, 2-sided). However, the number of patients with each individual disease was too small to conclude a prevalence of onychomycosis in conjunction with these individual cutaneous autoimmune diseases.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Maladies auto-immunes
/
Thaïlande
/
Femelle
/
Humains
/
Dermatoses vésiculobulleuses
/
Onychomycose
/
Adulte
/
Humidité
/
Immunosuppresseurs
Type d'étude:
Étude observationnelle
/
Étude de prévalence
/
Facteurs de risque
Pays comme sujet:
Asie
langue:
Anglais
Année:
2006
Type:
Article
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