Exfoliative cytology in screening for malignant and premalignant lesions in the buccal mucosa.
Ceylon Med J
;
1998 Dec; 43(4): 206-9
Article
Dans Anglais
| IMSEAR
| ID: sea-47423
ABSTRACT
OBJECTIVE:
To test the efficacy of exfoliative cytology in the detection of oral premalignant and malignant lesions.DESIGN:
Cytological diagnosis of lesions of the buccal mucosa assessed using histopathological diagnosis of the same lesions as the gold standard.SUBJECTS:
Patients with buccal lesions clinically diagnosed as leukoplakia (n = 91) and squamous cell carcinoma (SCC, n = 59), and healthy subjects (n = 40) in whom buccal mucosa appeared clinically normal.SETTING:
Oral and Maxillo-facial Unit, General Hospital, Kandy and Department of Pathology, Faculty of Medicine, University of Peradeniya.RESULTS:
A sensitivity of 77%, specificity of 100% and accuracy of 92% were obtained for leukoplakia. SCC gave a sensitivity of 94%, specificity of 100% and an accuracy of 95%.CONCLUSIONS:
Oral exfoliative cytology is a useful method for detecting oral premalignant and malignant lesions. Anucleated squames in a smear is non-diagnostic.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
États précancéreux
/
Humains
/
Leucoplasie buccale
/
Tumeurs de la bouche
/
Carcinome épidermoïde
/
Joue
/
Sensibilité et spécificité
/
Cytodiagnostic
/
Muqueuse de la bouche
Type d'étude:
Etude diagnostique
/
Étude de dépistage
langue:
Anglais
Texte intégral:
Ceylon Med J
Année:
1998
Type:
Article
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