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Comparison of some clinical and histological features of colorectal carcinoma occurring in patients below and above 40 years.
Ceylon Med J ; 2000 Dec; 45(4): 166-8
Article Dans Anglais | IMSEAR | ID: sea-48428
ABSTRACT

OBJECTIVE:

To determine the clinicopathological features of colorectal malignancies in Sri Lankan patients aged 40 years or younger, and to compare them with those of older patients.

METHODS:

The clinicopathological features of 60 colorectal malignancies which occurred in patients aged 40 years or younger were compared with 245 malignant colorectal tumours in older patients. These tumours had been diagnosed at a University Department of Pathology over 15 years.

RESULTS:

19.7% of colorectal malignancies occurred in patients aged 40 years or younger. (MaleFemale ratio = 1.61). The mean duration from onset of symptoms to diagnosis was 4.2 months. There was no statistically significant difference between young and old patients in the presenting symptoms, site of tumour and Dukes' staging of colorectal malignancies. A statistically significant proportion of tumours in young patients was mucoid (13.3%) or signet ring cell (5%) type. 3.3% of young patients with colorectal carcinoma gave a family history of similar malignancy. A history of predisposing conditions (ulcerative colitis) was present in 3.3% of young patients.

CONCLUSIONS:

The clinical presentation of colorectal malignancies in Sri Lankan patients below 40 years of age does not differ from that in older patients. Mucoid and signet ring cell carcinomas are commoner in the young.
Sujets)
Texte intégral: Disponible Indice: IMSEAR (Asie du Sud-Est) Sujet Principal: Pronostic / Sri Lanka / Sujet âgé / Femelle / Humains / Mâle / Carcinomes / Tumeurs colorectales / Incidence / Probabilité Type d'étude: Etude d'étiologie / Etude d'incidence / Étude observationnelle / Étude pronostique / Facteurs de risque Pays comme sujet: Asie langue: Anglais Texte intégral: Ceylon Med J Année: 2000 Type: Article

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Texte intégral: Disponible Indice: IMSEAR (Asie du Sud-Est) Sujet Principal: Pronostic / Sri Lanka / Sujet âgé / Femelle / Humains / Mâle / Carcinomes / Tumeurs colorectales / Incidence / Probabilité Type d'étude: Etude d'étiologie / Etude d'incidence / Étude observationnelle / Étude pronostique / Facteurs de risque Pays comme sujet: Asie langue: Anglais Texte intégral: Ceylon Med J Année: 2000 Type: Article