The pattern of hypogammaglobulinaemia in Sri Lankan children.
Ceylon Med J
;
2000 Jun; 45(2): 58-60
Article
Dans Anglais
| IMSEAR
| ID: sea-49049
ABSTRACT
OBJECTIVE:
To evaluate the prevalence of hypogammaglobulinaemia in Sri Lankan children who present with recurrent or severe bacterial infections.DESIGN:
A descriptive study.SETTING:
Medical Research Institute (MRI), Colombo.SUBJECTS:
100 children between the ages of four months to twelve years referred to the Department of Immunology, MRI, for evaluation of immune status during four years from 1993 to 1997. MEASUREMENTS Immunoglobulin G, A and M levels were measured using radial immunodiffusion technique.RESULTS:
22 out of 100 children had an underlying antibody deficiency, of whom IgA deficiency was the commonest (18 patients). Two patients had low IgG and A and elevated IgM levels, and they were diagnosed as having X linked-hyper-IgM syndrome. One patient had deficient IgA and IgM, and all three immunoglobulins were deficient in another.CONCLUSIONS:
Results indicate that IgA deficiency is the commonest immunodeficiency in Sri Lanka, which is comparable with studies done in the West. This study also shows the need to improve the standard of care in patients with immunodeficiency.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Sri Lanka
/
Humains
/
Immunoglobuline A
/
Immunoglobuline G
/
Immunoglobuline M
/
Enfant
/
Enfant d'âge préscolaire
/
Maladies transmissibles
/
Prévalence
/
Sujet immunodéprimé
Type d'étude:
Étude de prévalence
Pays comme sujet:
Asie
langue:
Anglais
Texte intégral:
Ceylon Med J
Année:
2000
Type:
Article
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