Antigeneic cross-reactivity between ICRC-bacilli and M. leprae--"in vitro" evaluation.
Indian J Lepr
;
1984 Apr-Jun; 56(2): 219-31
Article
Dans Anglais
| IMSEAR
| ID: sea-54495
ABSTRACT
Leucocyte migration inhibition, in presence of specific particulate antigen, is a good correlate of CMI. It can detect small differences in related antigens. In the present study, LMI was used to study the cross-reactivity between ICRC bacilli and M. leprae and also to examine the antigenic relationship amongst different ICRC isolates. The study showed a close antigenic cross-reactivity in lepromin and ICRC-in. LMI has brought out strain differences in two ICRC culture isolates, C-44 and C-75. The data appear to elucidate the possible strain specific antigenic relationship of M. leprae with its culture isolate e.g. ICRC strains. This may have important bearing on the development effective antileprosy vaccine for human use.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Rate
/
Femelle
/
Inhibition de la migration cellulaire
/
Vaccins antibactériens
/
Vaccin BCG
/
Réactions croisées
/
Lépromine
/
Lèpre
/
Leucocytes
/
Animaux
langue:
Anglais
Texte intégral:
Indian J Lepr
Thème du journal:
Tropical Medicine
Année:
1984
Type:
Article
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