Leucocyte migration inhibition response of Mycobacterium habana with sensitized animals and cells from leprosy patients.

ABSTRACT

Response of Mycobacterium habana sensitized mouse cells against habanin (sonicated extract) lepromin (Dharmendra) and tuberculin has been studied in the leucocyte migration inhibition test. The homologous antigenic response has evoked maximum inhibition as compared to heterologous antigens but close antigenic association has also been observed with lepromin and tuberculin. With human cells from leprosy patients these antigens have evoked analogous response indicating cross immunogenicity of M. habana with leprosy sensitized cells.