Clinical and electroneurophysiological assessment of leprosy patients on dapsone monotherapy--a two year follow-up study.
Indian J Lepr
;
1995 Apr-Jun; 67(2): 167-76
Article
Dans Anglais
| IMSEAR
| ID: sea-55475
ABSTRACT
Fifty-three persons with tuberculoid type of leprosy having a thickened nerve on one side and a clinically normal nerve on the contralateral side were studied before, during and after two years of therapy for electrophysiological abnormalities in apparently normal and in obviously thickened nerves. Twenty-seven patients had received treatment with dapsone 100 mg orally and 26 cases had received rifampicin therapy. It was found that there was no extension of anesthesia or diminution of motor power over a period of two years. There was no significant difference between the initial and final recordings of motor and sensory nerve conductions if aggregate figures were taken. However, taking individual cases, deterioration in nerve conduction (increased latency and decreased velocity) was found in two patients, of whom one had received dapsone and the other had received rifampicin.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Nerfs périphériques
/
Rifampicine
/
Femelle
/
Humains
/
Mâle
/
Lèpre tuberculoïde
/
Études prospectives
/
Études de suivi
/
Adolescent
/
Adulte
Type d'étude:
Essai clinique contrôlé
/
Étude observationnelle
/
Étude pronostique
langue:
Anglais
Texte intégral:
Indian J Lepr
Thème du journal:
Tropical Medicine
Année:
1995
Type:
Article
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