Role of free radicals in Plasmodium berghei infected Mastomys natalensis brain.
Indian J Exp Biol
;
1992 Dec; 30(12): 1193-6
Article
Dans Anglais
| IMSEAR
| ID: sea-56911
ABSTRACT
Lipid peroxide, lipid hydroperoxide, reduced glutathione, oxidised glutathione, lipofuscin contents and the activity of the enzyme superoxide dismutase were assessed in P. berghei infected M. natalensis brain. The results showed significant increase in the levels of lipid peroxides, lipid hydroperoxides and lipofuscin in brain subcellular fractions of P. berghei infected M. natalensis. Furthermore, a depressed superoxide dismutase activity was observed along with regulation in glutathione content. An elevated level of lipid peroxidation products along with depressed activity of scavengers in brain during malaria highlights the role of free radicals in malarial pathology.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Plasmodium berghei
/
Superoxide dismutase
/
Encéphale
/
Radicaux libres
/
Glutathion
/
Peroxydes lipidiques
/
Lipofuscine
/
Animaux
/
Paludisme
/
Muridae
langue:
Anglais
Texte intégral:
Indian J Exp Biol
Année:
1992
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS