Comparative immunopotentiating properties of saponin and incomplete Freund's adjuvant coupled to affinity purified larval antigen of Hyalomma anatolicum anatolicum.
Indian J Exp Biol
;
2002 Sep; 40(9): 1026-31
Article
Dans Anglais
| IMSEAR
| ID: sea-57021
ABSTRACT
Comparative immunostimulatory properties of saponin and incomplete Freund's adjuvant (IFA) were studied using affinity purified 39 kDa larval antigen of Hyalomma anatolicum anatolicum. Significant antibody response to 39 kDa antigen was detected in the sera of rabbits immunized with both 39 kDa plus saponin and 39 kDa plus IFA in comparison to their corresponding control animals. Insignificant differences were noted in the antibody response between the animals of two immunized groups. Upon challenge, the animals immunized with 39 kDa plus IFA rejected 76.2 +/- 9.7% of larvae and 45.8 +/- 4.1% of adults while in group of animals injected with 39 kDa plus saponin rejected 80.9 +/- 11.2% of larvae and 47.2 +/- 5.7% of adults.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Lapins
/
Saponines
/
Tiques
/
Immunoglobuline G
/
Bovins
/
Adjuvant Freund
/
Immunotoxines
/
Chromatographie d'affinité
/
Immunisation
/
Sérums immuns
langue:
Anglais
Texte intégral:
Indian J Exp Biol
Année:
2002
Type:
Article
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