Genotoxic effect of isoproturon (herbicide) as revealed by three mammalian in vivo mutagenic bioassays.
Indian J Exp Biol
;
1990 Sep; 28(9): 862-7
Article
Dans Anglais
| IMSEAR
| ID: sea-57253
ABSTRACT
Genotoxic effect of isoproturon was assessed by employing in vivo chromosomal aberration, micronucleus and sperm-shape abnormality assays. A significant dose-responsive mutagenic effect was observed in chromosome aberration and sperm-shape abnormality tests whereas in micronucleus assay the effect was significant only at the highest dose (200 mg/kg). Only the result for the chronic dose and the two different fixation times (6 and 48 hr) were not statistically significant. The results indicate the genotoxic property of isoproturon in mammalian in vivo test system.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Phénylurées
/
Spermatozoïdes
/
Mâle
/
Cellules de la moelle osseuse
/
Tests de micronucleus
/
Analyse de variance
/
Aberrations des chromosomes
/
Herbicides
/
Animaux
/
Méthylurées
langue:
Anglais
Texte intégral:
Indian J Exp Biol
Année:
1990
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS