Suppression of Con A induced lymphocyte transformation by sera from filarial patients with clinical manifestations.
Indian J Exp Biol
;
1991 Apr; 29(4): 352-4
Article
Dans Anglais
| IMSEAR
| ID: sea-57390
ABSTRACT
Reduced lymphocyte transformation to Wuchereria bancrofti microfilariae excretory-secretory antigen and Con A were observed in clinical filarial patients. Pre-incubation of normal human peripheral blood mononuclear cells with sera from filarial patients with clinical manifestations such as hydrocele and elephantiasis suppressed Con A induced responses. Effect of fractionated clinical filarial serum on Con A induced lymphocyte transformation showed that the inhibitory activity was associated with high molecular weight serum fraction.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Wuchereria bancrofti
/
Filariose lymphatique
/
Humains
/
Activation des lymphocytes
/
Cellules cultivées
/
Concanavaline A
/
Tolérance immunitaire
/
Animaux
langue:
Anglais
Texte intégral:
Indian J Exp Biol
Année:
1991
Type:
Article
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