Radiosensitizing effect of plumbagin on mouse melanoma cells grown in vitro.
Indian J Exp Biol
;
1996 Sep; 34(9): 857-8
Article
Dans Anglais
| IMSEAR
| ID: sea-57800
ABSTRACT
Mouse melanoma cells were treated with plumbagin, a naphthoquinone, from the plant Plumbago rosea at 0.5 microgram/ml (PI) for 60 min either alone or followed by 2 Gy gamma radiation (RT). Response to the different treatments was assessed by following the cell growth up to 5 days post treatment. PI alone produced a significant decrease in the cell count on days 3 and 4, whereas RT treatment significantly enhanced the growth inhibitory effect when compared to RT or PI alone. These findings suggests the radiosensitizing effect of PI on mouse melanoma cells in vitro, supporting the earlier in vivo findings.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Radiosensibilisants
/
Mélanome expérimental
/
Cellules cancéreuses en culture
/
Division cellulaire
/
Naphtoquinones
/
Animaux
/
Souris
/
Souris de lignée C57BL
langue:
Anglais
Texte intégral:
Indian J Exp Biol
Année:
1996
Type:
Article
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