Relationship between testosterone and hepatic lipids in mature male bonnet monkeys, Macaca radiata (Geoffroy).
Indian J Exp Biol
;
1991 Dec; 29(12): 1140-1
Article
Dans Anglais
| IMSEAR
| ID: sea-58260
ABSTRACT
Administration of testosterone propionate (TP; 1 mg/kg body weight/day; im, for 30 days) to mature male bonnet monkeys, decreased total lipids, glyceride glycerol and cholesterol concentrations in hepatic tissue. The decrease in glyceride glycerol was due to decrease in monoacyl and triacyl glycerol. Both, free and esterified cholesterol were decreased after testosterone administration. Eventhough, total phospholipid was not significantly altered, phosphatidylserine and cardiolipin were increased, due to testosterone administration. Testosterone inhibited NADP-isocitrate dehydrogenase activity in liver. The findings suggest that testosterone acts as a lipolytic hormone and its action may be direct through its specific receptors in liver.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Testostérone
/
Mâle
/
Métabolisme lipidique
/
Foie
/
Animaux
/
Macaca radiata
langue:
Anglais
Texte intégral:
Indian J Exp Biol
Année:
1991
Type:
Article
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