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De novo biosynthesis and localization of inhibin in marmoset (Callithrix jacchus) and rat epididymis.
Indian J Exp Biol ; 1991 Aug; 29(8): 715-20
Article Dans Anglais | IMSEAR | ID: sea-58887
ABSTRACT
Using specific polyclonal antibodies generated against a 13 Kd human testicular inhibin, immunocytochemical localization was carried out in epididymis of intact and castrated marmoset monkey and rat epididymis. Inhibin was found to be present in the cytoplasm of epithelial cells of caput, corpus and cauda epididymis. The intensity of staining and pattern of distribution did not change following castration. Further, the in vitro biosynthesis of inhibin studied by incorporating 3H-leucine and precipitating it with specific antibody indicated maximum biosynthesis in the corpus epididymis in case of marmosets and cauda in case of rats. Following castration in rats, the epididymal tissue still retained the capacity to biosynthesize inhibin. These studies indicate that marmoset and rat epididymis are capable of biosynthesizing/absorbing inhibin and whose synthesis does not depend on androgens.
Sujets)
Texte intégral: Disponible Indice: IMSEAR (Asie du Sud-Est) Sujet Principal: Rats / Mâle / Callithrix / Immunohistochimie / Épididyme / Inhibines / Animaux langue: Anglais Texte intégral: Indian J Exp Biol Année: 1991 Type: Article

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Texte intégral: Disponible Indice: IMSEAR (Asie du Sud-Est) Sujet Principal: Rats / Mâle / Callithrix / Immunohistochimie / Épididyme / Inhibines / Animaux langue: Anglais Texte intégral: Indian J Exp Biol Année: 1991 Type: Article