Electrokinetic behaviour of subpopulations of T lymphocytes in allografted mice.
Indian J Exp Biol
;
1992 Apr; 30(4): 281-3
Article
Dans Anglais
| IMSEAR
| ID: sea-59066
ABSTRACT
In AKR(H-2k) mice transplanted with DBA/2(H-2d) skin grafts, the mean electrophoretic mobilities (EPM) of total lymph node cells (LNC) and T cells were significantly reduced. Subpopulations of T lymphocytes, viz. CD4- (CD8- (CD4+) T cells were obtained by depletion treatment of T cells with monoclonal antibodies specific for these surface antigens and complement. Determination of EPM of these two subpopulations revealed that the electrokinetic change following immunostimulation equally afflicted these two subpopulations. These data thus confirmed that CD4+ as well as CD8+ T cells were activated in MHC unmatched allograft rejection.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Femelle
/
Activation des lymphocytes
/
Mouvement cellulaire
/
Sous-populations de lymphocytes T
/
Transplantation de peau
/
Animaux
/
Souris
/
Souris de lignée AKR
/
Souris de lignée DBA
langue:
Anglais
Texte intégral:
Indian J Exp Biol
Année:
1992
Type:
Article
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