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Steroid hormones retard aflatoxin-induced cytotoxicity.
Indian J Exp Biol ; 1993 Sep; 31(9): 780-1
Article Dans Anglais | IMSEAR | ID: sea-59354
ABSTRACT
Protective effect of sex steroid hormones on aflatoxin-induced cytotoxicity on RBC (hemolysis) was examined in vitro. Addition of aflatoxin (2 micrograms/ml) in RBC suspension caused significant increase in hemolysis. Concurrent addition of aflatoxin (2 micrograms/ml) and estradiolbenzoate (100-1200 pg/ml) in RBC suspension significantly retarded aflatoxin-induced hemolysis. Similarly, addition of aflatoxin (2 micrograms/ml) along with testosterone propionate (5-60 ng/ml) in RBC suspension retarded aflatoxin-induced hemolysis. Among the two synthetic hormones studied estradiolbenzoate was more potent than testosterone propionate.
Sujets)
Texte intégral: Disponible Indice: IMSEAR (Asie du Sud-Est) Sujet Principal: Testostérone / Humains / Adulte / Aflatoxines / Oestradiol / Hémolyse langue: Anglais Texte intégral: Indian J Exp Biol Année: 1993 Type: Article

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Texte intégral: Disponible Indice: IMSEAR (Asie du Sud-Est) Sujet Principal: Testostérone / Humains / Adulte / Aflatoxines / Oestradiol / Hémolyse langue: Anglais Texte intégral: Indian J Exp Biol Année: 1993 Type: Article