Specific activities of seminal vesicular phosphomonoesterases and Mg2+-,Ca2+- and Na+/K(+)-adenosine triphosphatases in hypo- and hyperthyroid albino rats.
Indian J Exp Biol
;
1993 Jul; 31(7): 587-9
Article
Dans Anglais
| IMSEAR
| ID: sea-59890
ABSTRACT
Hypothyroidism (surgical thyroidectomy) inhibited the activities of acid phosphatase and Mg(2+)-ATPase in seminal vesicular tissue and fluid and that of Ca(2+)- and Na+/K(+)-ATPases in fluid alone, and T4 supplementation restored normalcy in all, except acid phosphatase. Hyperthyroidism (T4 25 micrograms/100g body weight/day for 60 days, im) enhanced the activities of alkaline phosphatase and ATPases in seminal vesicular tissue and fluid, and decreased acid phosphatase activity in tissue alone. Withdrawal of T4 treatment from hyperthyroid rats (after 30 days) augmented the activity of ATPases in tissue and impaired the same in fluid, while phosphomonoesterases remained at hyperthyroid level. The results suggest specific responses of various seminal vesicular phosphatases to altered thyroid hormone status. Modification in the specific threshold of androgen/estrogen action on different phosphatases in seminal vesicles appears to be the plausible mechanism underlying these changes in hypo- and hyperthyroid conditions.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Rats
/
Vésicules séminales
/
Mâle
/
Albinisme
/
Rat Wistar
/
Ca(2/) Mg(2/)-ATPase
/
Calcium-Transporting ATPases
/
Adenosine triphosphatases
/
Sodium-Potassium-Exchanging ATPase
/
Phosphoric monoester hydrolases
langue:
Anglais
Texte intégral:
Indian J Exp Biol
Année:
1993
Type:
Article
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