Effects of gamma irradiation on histomorphology of some endocrine glands of the rain quail, Coturnix coromandelica (Gmelin).

ABSTRACT

Effects of single, whole-body 60Co-gamma irradiation in different doses (250 rad to 15 k rad) on histology of thyroid, adrenal and pancreatic islets of the rain quail were studied. A low dose of 250 rad failed to evoke any change in histology of the glands studied. Doses of 500 rad and 1 k rad resulted in hypoactivity of thyroid but could not affect adrenal and pancreatic islets. Exposure to 1.5 k rad and higher doses caused hyperplasia and hypertrophy of thyroid and hypertrophy of adrenal gland. Thyroid was injured by heavy irradiation. Doses up to 3 k rad did not bring about any change in islet cells, however, higher doses resulted in degenerative changes in islet cells. alpha-islets were affected by 7 and 15 k rad but necrotic changes in beta-islets were observed only after exposure to 15 k rad. The results indicate that thyroid is the most sensitive and pancreatic islet, highly resistant to gamma radiation.