Pre-clinical toxicity evaluation of leaf-stalk extractive of Piper betle Linn. in rodents.
Indian J Exp Biol
;
2000 Apr; 38(4): 338-42
Article
Dans Anglais
| IMSEAR
| ID: sea-60471
ABSTRACT
Studies on pre-clinical toxicity were undertaken to determine the haematological and biochemical changes after administration of alcoholic extract of leaf-stalk of P. betle in rats and mice. Acute and chronic toxicity experiments were performed on mice and rats according to WHO protocol. Different doses of plant extractive were administered for toxicity studies on short and long term basis. Haematological, biochemical profiles and enzymatic studies (transaminases and phosphatases) indicated that the drug (plant extractive) was devoid of toxicity.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Taille d'organe
/
Plantes médicinales
/
Rats
/
Femelle
/
Mâle
/
Extraits de plantes
/
Magnoliopsida
/
Évaluation préclinique de médicament
/
Enzymes
/
Rein
Type d'étude:
Guide de pratique
langue:
Anglais
Texte intégral:
Indian J Exp Biol
Année:
2000
Type:
Article
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