Relative potentiality of some contragestational agents on trauma induced deciduoma formation in immature rats.
Indian J Exp Biol
;
1997 Jun; 35(6): 589-93
Article
Dans Anglais
| IMSEAR
| ID: sea-60966
ABSTRACT
Relative progestational and antiprogestational profile of four contragestational agents, viz. RMI-12,936, RU-38,486, STS-557 and WIN-32,729, known to possess either or both the properties in other test systems, was determined in immature rats using deciduoma induction as marker. The deciduoma was produced by needle traumatization in one of the uterine horn, and the extent of stimulation was analysed, both macro and microscopically, against the control nontraumatized horn. The results indicated that the agents which demonstrated better potentiality(ies) as progestational and/or antiprogestational in this bioassay exhibit contraceptive efficacy at relatively lower doses as compared to those that showed mild to moderate potentiality.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Progestines
/
Rats
/
Utérus
/
Femelle
/
Rat Sprague-Dawley
/
Caduques
/
Animaux
langue:
Anglais
Texte intégral:
Indian J Exp Biol
Année:
1997
Type:
Article
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