Effect of picroliv on glutathione metabolism in liver and brain of Mastomys natalensis infected with Plasmodium berghei.
Indian J Exp Biol
;
1992 Aug; 30(8): 711-4
Article
Dans Anglais
| IMSEAR
| ID: sea-61476
ABSTRACT
Administration of picroliv, the active principle from Picrorhiza kurrooa, at a dose of 6 mg/kg, po for two weeks showed significant protection against changes in liver and brain glutathione metabolism of Plasmodium berghei infected Mastomys natalensis. The depletion of reduced glutathione level and inhibition of glutathione-S-transferase, glutathione reductase and glutathione peroxidase activities due to P. berghei infection were markedly recovered by picroliv. The increased levels of lipid peroxidation products in damaged tissues were also reduced along with the recovery of glutathione metabolism.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Plasmodium berghei
/
Acide vanillique
/
Encéphale
/
Mâle
/
Extraits de plantes
/
Peroxydation lipidique
/
Cinnamates
/
Glutathion
/
Hétérosides
/
Foie
langue:
Anglais
Texte intégral:
Indian J Exp Biol
Année:
1992
Type:
Article
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