Antimutagenic effects of polyphenols isolated from Terminalia bellerica myroblan in Salmonella typhimurium.
Indian J Exp Biol
;
1996 Feb; 34(2): 98-102
Article
Dans Anglais
| IMSEAR
| ID: sea-62174
ABSTRACT
Antimutagenic effect of 2 polyphenolic fractions isolated from T. bellerica in TA98 and TA100 strains of S. typhimurium against 2AF, NPD and 4NQNO has been characterized. Both the fractions were significantly effective against S9-dependent 2AF; less effective against NPD and almost not effective against 4NQNO in TA100 strain. Using 13C-NMR spectral analysis, the TB-3 fraction, which was significantly more effective against 2AF compared to TB-4, was found to be a mixture of 3 tannins while TB-4 was non-tannin fraction. Interaction of polyphenols with S9 proteins may be the probable cause of inhibitory effect of these polyphenols, though the possibility of other mechanisms cannot be ruled out.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Phénols
/
Polymères
/
Salmonella typhimurium
/
Spécificité d'espèce
/
Flavonoïdes
/
Antimutagènes
/
Fruit
langue:
Anglais
Texte intégral:
Indian J Exp Biol
Année:
1996
Type:
Article
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