Characterization of toxin from cheilanthes fern and its effect on lymphocyte proliferation and DNA fragmentation.
Indian J Exp Biol
;
2001 Oct; 39(10): 1065-7
Article
Dans Anglais
| IMSEAR
| ID: sea-62395
ABSTRACT
Thin layer chromatography of aqueous extract of whole Cheilanthesfarinosa fern indicated the presence of ptaquiloside or ptaquiloside like compound, coinciding Rf values with that of Pterosin B standard. HPLC analysis revealed the presence of 26.3 mg/kg ptaquiloside. In vitro studies of the aqueous extract on lymphocyte culture revealed a correlation between stimulative indices and concentration of aqueous extract. Stimulation in lymphocyte proliferation was in order of bracken > cheilanthes > ConA> ptaquiloside standard. On incubation of lymphocyte with aqueous extract of ferns, no DNA damage was observed in isolated DNA.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Végétaux toxiques
/
Sels de tétrazolium
/
Bovins
/
Extraits de plantes
/
Activation des lymphocytes
/
Lymphocytes
/
Chromatographie en phase liquide à haute performance
/
Chromatographie sur couche mince
/
Fougères
/
Fragmentation de l'ADN
langue:
Anglais
Texte intégral:
Indian J Exp Biol
Année:
2001
Type:
Article
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