Androgenic control of hepatic mitochondrial metabolism in an apoda, Gegenophis carnosus (Beddome).
Indian J Exp Biol
; 1991 Nov; 29(11): 1027-30
Article
de En
| IMSEAR
| ID: sea-62432
In vivo administration of testosterone significantly stimulated the activities of cytochrome oxidase, alpha-glycerophosphate dehydrogenase (alpha-GPDH), succinate dehydrogenase (SDH) and adenosine triphosphatase (Mg2+ ATPase), in mitochondria isolated from the liver of G. carnosus. Administration of dehydroepiandrosterone and androstenedione while significantly stimulated the activities of cytochrome oxidase and alpha-GPDH, did not change that of SDH and Mg2+ ATPase. Simultaneous injections of testosterone and actinomycin D or chloramphenicol prevented the testosterone-stimulated activities of all the oxidative enzymes studied. The results clearly document the important stimulatory role of androgens in the regulation of hepatic mitochondrial metabolism in G. carnosus.
Texte intégral:
1
Indice:
IMSEAR
Sujet Principal:
Oxydoréduction
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Testostérone
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Mâle
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Mitochondries du foie
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Inhibiteurs de la synthèse protéique
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Amphibiens
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Animaux
langue:
En
Texte intégral:
Indian J Exp Biol
Année:
1991
Type:
Article