Immunohistochemical demonstration of mycobacterial antigens in intracranial tuberculoma.
Indian J Exp Biol
;
1991 Jul; 29(7): 641-4
Article
Dans Anglais
| IMSEAR
| ID: sea-62444
ABSTRACT
Mycobacterial antigens have been demonstrated immunohistochemically in the paraffin sections of 10 intracranial tuberculous granulomas and the results were compared with the detection of acid fast bacilli by conventional Ziehl-Neelsen method. In none of the 10 specimens, acid fast bacilli were demonstrated while mycobacterial antigens were characterised as diffusely staining granular brownish-pink material within the cytoplasm of giant cells and macrophages. In 14 specimens of granulomatous lesions due to non-tuberculous aetiology, immunohistochemical stains were negative for mycobacterial antigen. Thus demonstration of mycobacterial antigen will be not only useful in establishing mycobacterial aetiology of a caseating intracranial granuloma but also can be used as an alternative method to the conventional Ziehl-Neelsen method.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Coloration et marquage
/
Tuberculome
/
Encéphalopathies
/
Humains
/
Techniques immunoenzymatiques
/
Granulome
/
Mycobacterium tuberculosis
/
Antigènes bactériens
langue:
Anglais
Texte intégral:
Indian J Exp Biol
Année:
1991
Type:
Article
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