Impact of hypercholesterolemia on in vitro toxicity of N-nitrosodiethylamine: effect on lipidperoxidation of blood and tissue.
Indian J Exp Biol
;
2002 Sep; 40(9): 1071-3
Article
Dans Anglais
| IMSEAR
| ID: sea-63130
ABSTRACT
In vitro treatment of erythrocytes of normal and hypercholesterolemic rats with N-nitrosodiethylamine (NDEA), an important carcinogen frequently present in human environment and food chain resulted in a marginal increase in osmotic fragility of erythrocytes without affecting their antioxygenic potential as evidenced by insignificant effect on lipid peroxidation (LPO). However, (LPO) of all the tissues (heart, lung, liver, kidney and spleen) increased significantly on in vitro treatment with NDEA. The effects were different in different tissues under different dietary conditions
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Fragilité osmotique
/
Rats
/
Rate
/
Mâle
/
Peroxydation lipidique
/
Compléments alimentaires
/
N-Éthyl-N-nitroso-éthanamine
/
Agents alcoylants
/
Érythrocytes
/
Coeur
langue:
Anglais
Texte intégral:
Indian J Exp Biol
Année:
2002
Type:
Article
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