Liver function and plasma protein metabolism in rodent model of filariasis.
Article
Dans Anglais
| IMSEAR
| ID: sea-64551
ABSTRACT
Rodent model of filariasis was developed by infecting Wistar rats with Litomosoides carinii. Liver function tests, plasma protein concentrations, and synthesis rates of liver-formed proteins were estimated in these rats at 63 and 90 days post-infection. At 63 days post-infection, aspartate aminotransferase and alkaline phosphatase were significantly increased. Alanine aminotransferase, plasma total proteins and plasma albumin were in the normal range. However, at 90 days post-infection all these parameters were affected, reflecting progressive liver involvement. Hypoalbuminemia at 90 days post-infection did not appear to be due to decreased synthesis rate, indicating higher catabolism and/or altered distribution in pools.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Rats
/
Lignées consanguines de rats
/
Mâle
/
Protéines du sang
/
Arvicolinae
/
Filarioses
/
Foie
/
Parasitoses hépatiques
/
Animaux
langue:
Anglais
Année:
1989
Type:
Article
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