Evaluation of plasma serotonin concentration in acute appendicitis.
Article
Dans Anglais
| IMSEAR
| ID: sea-64643
ABSTRACT
BACKGROUND:
Due to lack of reliable biochemical/radiological markers, the diagnosis of acute appendicitis is based only on clinical features.METHODS:
We estimated plasma serotonin levels in 48 patients with acute appendicitis (histologically proven), 27 patients with abdominal pain of other etiologies, and 20 healthy controls.RESULTS:
The plasma serotonin levels were (mean +/- SD) 36.6 +/- 12.5 nmol/L, 12.5 +/- 3.6 nmol/L and 10.4 +/- 3.5 nmol/L in the three groups, respectively. The levels in patients with acute appendicitis were significantly higher (p < 0.001) than in the other groups, giving 93.8% sensitivity and 95.7% specificity to the test.CONCLUSION:
Plasma serotonin level is a reliable marker of acute appendicitis, especially in the first 48 hours.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Appendicite
/
Humains
/
Marqueurs biologiques
/
Sérotonine
/
Douleur abdominale
/
Maladie aigüe
/
Valeur prédictive des tests
/
Sensibilité et spécificité
/
Diagnostic différentiel
Type d'étude:
Essai clinique contrôlé
/
Etude diagnostique
/
Étude pronostique
langue:
Anglais
Année:
1997
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS