Percutaneous sonography-guided fine needle aspiration biopsy of colonoscopic biopsy-negative colonic lesions.
Article
Dans Anglais
| IMSEAR
| ID: sea-64751
ABSTRACT
BACKGROUND:
Pre-operative tissue diagnosis with colonoscopy is not always possible in patients with colonic lesions.OBJECTIVE:
To study the usefulness and efficacy of percutaneous ultrasound-guided aspiration biopsy of colonic lesions.METHODS:
Fifty consecutive patients with colonic lesions in whom colonoscopic brush cytology and biopsy were either negative or the lesion was not accessible on colonoscopy on two attempts, underwent percutaneous ultrasound-guided fine-needle aspiration biopsy. The results were compared with surgical findings.RESULTS:
Fine-needle aspiration biopsy revealed adenocarcinoma in 40 patients; one had lymphoma, 2 had tuberculosis, 2 had abscess and 5 patients had negative aspiration. Forty-eight patients (excluding 2 with tuberculosis) underwent laparotomy and the diagnoses on aspiration biopsy were confirmed. Of the 5 negative aspirations, 3 had adenocarcinoma, one had tuberculosis and one intussusception. Thus, we had sensitivity of 91.8%, specificity of 100%, predictive value of positive results 100%, predictive value of negative results 20%, and percentage of false negative results 8.1%. Two patients developed complications--hemorrhage into the peritoneum and sepsis due to perforation at the site of aspiration; both survived after surgery.CONCLUSION:
Percutaneous ultrasound-guided aspiration biopsy may be attempted for diagnosis of colonic lesions in situations where it may be the only means of obtaining a cytological diagnosis before surgery.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Ponction-biopsie à l'aiguille
/
Femelle
/
Humains
/
Mâle
/
Adénocarcinome
/
Valeur prédictive des tests
/
Échographie
/
Sensibilité et spécificité
/
Coloscopie
/
Côlon
Type d'étude:
Etude diagnostique
/
Étude pronostique
langue:
Anglais
Année:
1999
Type:
Article
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