Evaluation of safety and efficacy of azithromycin in lower respiratory tract infections (LRTI)
Article
Dans Anglais
| IMSEAR
| ID: sea-66618
ABSTRACT
Azithromycin was given to 55 cases of lower respiratory tract infections in the doses of 500 mg on day 1, followed by 250 mg on days 2-5. It produced bacteriological cure in 70.8% patients and clinical cure or improvement in 69.09% of patients. 4.27% of patients had throat colonisation with new organisms, of which 9.09% needed a second antibiotic. The drug was well tolerated and minor side effects were noted. Gastrointestinal disturbances (16.36%) headache and giddiness (14.55%), rash (3.64%) were the noted side effects. Reduction of platelet count by 50% occurred in 12.29% of the cases compared to 0.2% reported earlier. But this thrombocytopenia was clinically not significant, as it did not cause any symptoms.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Infections de l'appareil respiratoire
/
Femelle
/
Humains
/
Mâle
/
Adolescent
/
Résultat thérapeutique
/
Azithromycine
/
Études d'évaluation comme sujet
/
Inde
/
Antibactériens
Type d'étude:
Etude diagnostique
/
Études d'évaluation
Pays comme sujet:
Asie
langue:
Anglais
Année:
1996
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS