Role of metronidazole in radiation therapy (a review of 717 cancer cases).
Indian J Med Sci
;
1994 May; 48(5): 111-6
Article
Dans Anglais
| IMSEAR
| ID: sea-66898
ABSTRACT
The presence of Hypoxic cells in a tumor decreases their radiosensitivity; which blocks the efficacy of external tele cobalt irradiation. So a study was undertaken in various cancer patients to observe the role of metrnidazole as a selective radiosensitizer. 717 cancer cases were enlisted and were divided into a study and control group. The study group were given metronidazole at a dose of 2 grams orally, 4 hours before each irradiation, (5 days in a week) for 6-7 weeks. The control group were devoid of it. After completion of the treatment, as well as, after 3 years follow-up, it was observed that the patients receiving metronidazole had better treatment response and more number of recurrence free years. Since it is a cheaper drug it can be used freely in the form of a potential radiosensitizer, for external irradiation therapy.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Femelle
/
Humains
/
Tumeurs de la bouche
/
Tumeurs du col de l'utérus
/
Métronidazole
/
Tumeurs
langue:
Anglais
Texte intégral:
Indian J Med Sci
Année:
1994
Type:
Article
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