Effects of amantadine on modification of dopamine dependent behaviours by molindone.
Indian J Med Sci
;
2000 Aug; 54(8): 321-4
Article
Dans Anglais
| IMSEAR
| ID: sea-67835
ABSTRACT
Amantadine, a dopamine agonist is reported to act by releasing dopamine from the dopaminergic nerve terminals as an anti-Parkinsonian drug. In the present behavioural study in the rat, molindone-induced catalepsy and ptosis, which are dopamine dependent-behaviors are reversed by amantadine. Amantadine has also revered molindone-induced inhibition of traction response in mice. Our study indicates that amantadine, like other DA agonists, e.g. amphetamine and apomorphine can antagonize or even reverse the neuroleptic induced dopaminergic behaviors.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Rats
/
Lignées consanguines de rats
/
Valeurs de référence
/
Spécificité d'espèce
/
Comportement animal
/
Blépharoptose
/
Mâle
/
Agents dopaminergiques
/
Amantadine
/
Dopamine
langue:
Anglais
Texte intégral:
Indian J Med Sci
Année:
2000
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS