Genetic marker in juvenile diabetic retinopathy.
Indian J Ophthalmol
;
1989 Jan-Mar; 37(1): 2-4
Article
Dans Anglais
| IMSEAR
| ID: sea-69556
ABSTRACT
Thirty five patients with insulin dependent diabetes mellitus (IDDM) were investigated for development of retinal microangiopathy by fluorescein angiography. HLA typing (A,B.C antigens) was done as a genetic marker. There was no statistically significant difference in the frequency of HLA antigens between patients without retinopathy (Gr.I) and with retinopathy (Gr.II) Frequency of various HLA antigens did not differ significantly in the mild and severe retinopathy groups or in comparison with controls. HLA B8 was significantly over represented in the patients of IDDM as a single group (GrI + II) when compared with controls (26% vs 8%). HLA profile was not a predictor of either the development or the severity of retinopathy in IDDM.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Femelle
/
Humains
/
Mâle
/
Marqueurs génétiques
/
Adolescent
/
Adulte
/
Rétinopathie diabétique
langue:
Anglais
Texte intégral:
Indian J Ophthalmol
Année:
1989
Type:
Article
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