Retinopathy of prematurity in Asian Indian babies weighing greater than 1250 grams at birth: ten year data from a tertiary care center in a developing country.
Indian J Ophthalmol
;
2007 Sep-Oct; 55(5): 331-6
Article
Dans Anglais
| IMSEAR
| ID: sea-71534
ABSTRACT
BACKGROUND:
Retinopathy of prematurity (ROP) is an important cause of childhood blindness in developing countries.AIM:
To report the spectrum of ROP and associated risk factors in babies weighing > 1250 g at birth in a developing country. SETTING ANDDESIGN:
Institutional, retrospective, non-randomized, observational clinical case series. MATERIALS ANDMETHODS:
Retrospective analysis (10 years) of 275 eyes (138 babies) with ROP. STATISTICALANALYSIS:
Qualitative data with the Chi-square test. Quantitative data using the unpaired t test or the ANOVA and further tested using multivariate logistic regression.RESULTS:
The mean birth weight was 1533.9 g (range 1251 to 2750 g) and the mean period of gestation was 30.9 weeks (range 26 to 35). One hundred and twenty-four of 275 eyes (45.1%) had threshold or worse ROP. Risk factors for threshold or worse disease were, 'outborn babies' ( P P = 0.007) and exchange transfusion ( P = 0.003). The sensitivity of the American and British screening guidelines to pick up threshold or worse ROP in our study group was 82.4% and 77.4% respectively.CONCLUSIONS:
Severe ROP is often encountered in babies weighing greater than 1250 g at birth in developing countries. Western screening guidelines may require modifications before application in developing countries.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Rétinopathie du prématuré
/
Humains
/
Nouveau-né
/
Incidence
/
Analyse multifactorielle
/
Études rétrospectives
/
Facteurs de risque
/
Études de suivi
/
Nourrisson très faible poids naissance
/
Asiatiques
Type d'étude:
Etude d'étiologie
/
Guide de pratique
/
Etude d'incidence
/
Étude observationnelle
/
Étude pronostique
/
Recherche qualitative
/
Facteurs de risque
Pays comme sujet:
Asie
langue:
Anglais
Texte intégral:
Indian J Ophthalmol
Année:
2007
Type:
Article
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