Cell mediated immune status in carcinoma breast.
Indian J Pathol Microbiol
;
1991 Jan; 34(1): 1-6
Article
Dans Anglais
| IMSEAR
| ID: sea-74764
ABSTRACT
Thirty six cases of carcinoma breast were subjected to the assessment of CMI status by estimating different T lymphocyte parameters. The mean TPLC, T% and TTC in case of carcinoma were 1955/mm3 blood, 41% and 825/mm3 blood respectively which are evidently depressed than that of controls. This depression is progressive and clinical stage related, the least being in stage I and the most being in stage IV. The infiltrating varieties revealed a significant depression of T lymphocyte values than the non-infiltrating ones. Among the infiltrating types, IDC (T-38.9%) and Muc. Ca (T-29.1%) revealed most significant depression, thereby indicating worst prognosis. Six cases of IDCS, 2 cases of Medullary Ca and a solitary case of comedo Ca revealed a significant lymphocyte infiltration into the tumour cell mass proper. There was a depressed lymphocyte values but of lesser magnitude indicating a better prognosis. 6 cases without metastasis (clinical St. I) showed a lesser degree of depressed CMI than the cases with metastasis.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Tumeurs du sein
/
Femelle
/
Humains
/
Carcinomes
/
Lymphocytes T
/
Carcinome intracanalaire non infiltrant
/
Adénocarcinome mucineux
/
Immunité cellulaire
/
Numération des leucocytes
langue:
Anglais
Texte intégral:
Indian J Pathol Microbiol
Année:
1991
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS