AgNOR counts are not altered in alcoholic cirrhosis.
Indian J Pathol Microbiol
;
2003 Apr; 46(2): 170-2
Article
Dans Anglais
| IMSEAR
| ID: sea-75409
ABSTRACT
One hundred and two liver biopsy specimens were stained for Argyrophilic nucleolar organizer regions and associated proteins to assess its utility in differentiating normal, cirrhotic and neoplastic liver tissue. A statistically significant (p < 0.001) difference was observed between mean AgNOR counts of normal (1.53 +/- 0.4), post-hepatitic cirrhosis (3.65 +/- 0.53) and hepatocellular carcinoma (7.94 +/- 1.18). In contrast the mean AgNOR count of biopsies with alcoholic cirrhosis (1.57 +/- 0.06) was significantly less (p < 0.001) than post-hepatitic cirrhosis and was similar to that of normal liver tissue. It is concluded that AgNORs can act as a good adjuvant to histology in diagnosing liver diseases especially in differentiating post-hepatitic and alcoholic cirrhosis.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Argent
/
Coloration et marquage
/
Humains
/
Études cas-témoins
/
Carcinome hépatocellulaire
/
Hépatite
/
Foie
/
Cirrhose du foie
/
Cirrhose alcoolique
/
Tumeurs du foie
Type d'étude:
Étude observationnelle
/
Facteurs de risque
langue:
Anglais
Texte intégral:
Indian J Pathol Microbiol
Année:
2003
Type:
Article
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