Serum resistance of Escherichia coli strains causing urinary tract infection and diarrhoea in relation to alpha haemolysin production and O type.
Indian J Pathol Microbiol
;
2003 Jul; 46(3): 504-6
Article
Dans Anglais
| IMSEAR
| ID: sea-75758
ABSTRACT
A total of 46 alpha-hemolytic and 40 non-hemolytic clinical isolates of Escherichia coli were collected from pediatric patients with urinary tract infection and diarrhoea. Of 39 (84.7%) alpha-hemolytic strains and 27 (67.5%) non-hemolytic strains were resistant to 10% serum and there was no significant difference between urinary and stool isolates. On the contrary when 100% serum was used, 22 (47.8%) of the alpha-hemolytic and 7 (17.5%) of the non-hemolytic strains were resistant (p<0.01). and significantly greater resistance was found in urinary tract infection than from the stool samples (47% versus 24%, p<0.01). Serum resistance was higher in serogroups O6, O18 and O75. Production of alpha-hemolysin was more frequent in serogrops O2, O6, O8, O18 and O75. Thus, the resistance to human serum can determine clinical significance of Escherichia coli from different sources and alpha-hemolysin contributes to the virulence of Escherichia coli in initiation and perpetuation of clinical infection.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Infections urinaires
/
Virulence
/
Activité bactéricide du sang
/
Humains
/
Techniques de typage bactérien
/
Antigènes O
/
Protéines Escherichia coli
/
Diarrhée
/
Escherichia coli
/
Infections à Escherichia coli
langue:
Anglais
Texte intégral:
Indian J Pathol Microbiol
Année:
2003
Type:
Article
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