Disseminated intravascular coagulation: current concepts.
Indian J Pediatr
;
2008 Jul; 75(7): 733-8
Article
Dans Anglais
| IMSEAR
| ID: sea-82328
ABSTRACT
Disseminated intravascular coagulation (DIC) is an acquired disorder in which normal hemostatic balance is disturbed. There is excessive thrombin formation leading to fibrin deposition in microcirculation and consequent ischemic organ damage. The etiology is multifactorial. A number of medical, surgical, oncological and obstetrical conditions can cause DIC. The diagnosis is essentially clinical supported by laboratory parameters and a scoring system based on these. The mainstay of treatment is correction of underlying cause and hemostatic support with replacement of coagulation factors. The role of heparin therapy and other therapeutic options including activated protein C, antithrombin III etc. have also been discussed.
Texte intégral:
Disponible
Indice:
IMSEAR (Asie du Sud-Est)
Sujet Principal:
Inhibiteurs de protéases
/
Humains
/
Protéine C
/
Héparine
/
Antithrombine-III
/
Maladie aigüe
/
Maladie chronique
/
Transfusion de composants du sang
/
Coagulation intravasculaire disséminée
/
Lipoprotéines
langue:
Anglais
Texte intégral:
Indian J Pediatr
Année:
2008
Type:
Article
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